Method for impregnating a drug or a composition of drugs in ophthalmic articles

摘要

Method for impregnating a drug or a composition of drugs in ophthalmic articles.This invention describes a method of impregnation of a drug or a composition of drugs in ophthalmic articles with the aim of developing systems for controlled release of drugs.Mainly for the treatment of glaucoma and other diseases of the eye. Articles 18 can be, for example, contact lenses.The drug, or combination of drugs, is dissolved in a fluid film, or a mixture of fluid film in a liquid state, lu00faquido sub critical.The gaseous or supercritical CO solvents and can be added in order to increase the solubility of the drugs in the fluid film.The mixture is subsequently brought into contact with the article eye. This process can be performed in a single step or in two consecutive steps.The impregnation can be carried out in finished or semi-finished ophthalmic articles.