The bacterium belonging to the genus Bacillus or to the genus Escherichia, and methods to produce a nucleosu00ecdeo purine, to produce a nucleotu00ecdeo purine and to produce acid 5 '- guanu00eclico

摘要

The bacterium belonging to the genus Bacillus or to the genus Escherichia, and methods to produce a nucleosu00ecdeo purine, to produce a nucleotu00ecdeo purine and to produce acid 5 '- guanu00eclico are provided methods to produce analogues of purine nucleoside base, purine and nucleot u00eddeos purine, such as acid, inosine and 5 '- inosu00ednico,Using bacteria belonging to the genus which include bacillus, Escherichia, the productivity of said bacterium purine is improved by increasing the activity of the protein YdhL. Also described is the sequence of amino acids of protein YdhL of Bacillus amyloliquefaciens and gene encoding the same.