Nanopartu00ecculas pegiladas for transport of biologically active molecules, pharmaceutical composition, liofilizato constituting nanopartu00ecculas pegiladas and preparation process of nanopartu00ecculas pegiladas

摘要

Nanopartu00ecculas pegiladas Pope transport of biologically active molecules, pharmaceutical composition, liofilizato constituting nanopartu00ecculas pegiladas and preparation process of nanopartu00ecculas pegiladas relates to nanoparticles forming a biodegradable polymer.Preferably the methyl vinyl ether copolymer and the malu00e9ico anhydride (PVM / MA) and a polyethylene glycol or derivatives of this; these nanoparticles are easy to produce and provide excellent characteristics of bioadesu00e3o, size and zeta potential.Therefore suitable for administration of active molecules; the selection of the type of polyethylene glycol used in its production allows modular properly the characteristics of these nanoparticles.That can be used to form advantageous according to the type of drug to be transported and / or method of administration of the pharmaceutical formulation; the pegilau00e7u00e3o is performed by simple incubation for a short period of time of the two macromolecules in question,Without the need to make use of organic solvents with high toxicity and long and laborious processes of organic synthesis; in addition, the process of pegilau00e7u00e3o may be involved in the process of encapsulation of biologically active molecules.