isolated antibody or antigen binding region thereof, hybridoma cell, transfectoma cell, monoclonal antibody or antigen binding region thereof, transgenic non-human animal, method for producing an antibody or antigen binding region thereof, composition use of antibody or antigen binding region, isolated polypeptide, immunoassay, and method for identifying a compound

摘要

ISOLATED ANTIBODY OR ANTIGEN ANTIGEN BLOOD ANTIGEN, HYDROGEN ANTIGEN, ANTIGEN, ANTIGEN ORIGINAL ANTIGEN, ANTIGEN, ANTIGEN, ANTIGEN, ANTIGEN, ANTIGEN, ANTIGEN, ANTIGEN, ANTIGEN, AND CELLS PHARMACEUTICAL, ANTIBODY USE OR ANTIBODY BINDING REGION, ISOLATED POLYPEPTIDE, IMMUNOASSAGE, AND, METHOD TO IDENTIFY A COMPOUND Anti-CD148 antibodies and antigen-binding regions, as well as pharmaceutical compositions comprising regions and antibodies thereof antigen, are described. Methods of using such antibodies and antigen binding region to bind CD148 epitopes and activate CD148 function, such as inhibition of angiogenesis, are also described. Epitopes that can be used to activate CDI 48 function and anti-angiogenesis activity are also described, as well as methods of identifying compounds that can bind them.