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A vesicle Preparation produced by genetic engineering from a modified Strain of a Gram negative bacterium

机译:通过遗传工程从革兰氏阴性细菌的改良菌株生产的囊泡制剂

摘要

? A Gall bladder Preparation obtained by genetic engineering from a modified Strain of a Gram negative bacterium which is characterized in that the preparation can be obtained using the following Process: (a) a process of bottom-up Regulation of the expression of Protective OMP antigens within the Gall bladder Preparation comprising the steps of identifying diCho antigen, a modified by Genetic Engineering bacterial Strain rnu00e1s looking to introduce a strong Promoter Sequence upstream of the gene encoding the Antigen so that the Gene is expressed at a higher level than in the gallbladder is not modified, and has CER vesicles From This strain. File = " EMI 06009341 _ 1" id = "1" mfi = Jpeg i Wi = = 50 50
机译:?通过遗传工程从革兰氏阴性细菌的改良菌株中获得的胆囊制剂,其特征在于,可以使用以下方法获得该制剂:(a)自下而上调节内保护性OMP抗原表达的过程。胆囊制剂,包括鉴定diCho抗原的步骤,这是由基因工程细菌菌株rnn修饰的,目的是在编码抗原的基因上游引入强启动子序列,从而使该基因的表达水平高于胆囊中的表达水平没有被修饰,并且具有来自该菌株的CER囊泡。文件= “ = 50 50

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