AMINOPYRIDINE DERIVATIVES AS SELECTIVE D3 AGRONISTS - DOPAMINE RECEPTORS

摘要

The present invention provides compounds of formula (I), which are a class of dopamine agonists, more specifically, a class of agonists that are more selective for D3 compared to D2. These compounds are useful for the treatment and / or prevention of sexual dysfunction, for example female sexual dysfunction (FSD), in particular female sexual arousal disorder (FSAD), hypoactive sexual desire disorder (HSDD; lack of interest in sex), female orgasmic disorder (FOD; failure to achieve orgasm); and male sexual dysfunction, in particular male erectile dysfunction (MED). Male sexual dysfunction, when referred to here, means that it includes ejaculatory disorders such as premature ejaculation, anorgasmia (inability to achieve orgasm) or attraction disorders such as hypoactive sex drive disorder (HSDD; lack of interest in sex). These compounds are also useful in the treatment of neuropsychiatric disorders and neurodegenerative disorders.