首页> 外国专利> USE OF COMPOUNDS HAVING THE BIOLOGICAL ACTIVITY OF VASOACTIVE INTESTINAL PEPTIDE FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

USE OF COMPOUNDS HAVING THE BIOLOGICAL ACTIVITY OF VASOACTIVE INTESTINAL PEPTIDE FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

机译:具有血管活性肠肽生物活性的化合物在治疗慢性阻塞性肺疾病中的应用

摘要

The present invention relates to the use of peptides and pharmaceutical compositions containing said peptides, that are highly biologically and pharmacologically active as therapeutic drugs for the treatment of diseases related to chronic obstructive pulmonary disease (COPD) which is preferably not correlated to pulmonary hypertension symptoms. Furthermore, the invention discloses the use of said peptides for another lung disease which is acute (adult) respiratory distress syndrome (ARDS). It could be shown that the known naturally occurring peptides "vasoactive intestinal peptide (VIP)" and "pituitary adenylate cyclase-activating polypeptide (PACAP)" as well as analogues or derivatives of VIP and PACAP can be successfully used for the treatment of said diseases.
机译:本发明涉及具有高生物学和药理学活性的肽和含有所述肽的药物组合物作为治疗药物的用途,所述药物优选与慢性阻塞性肺疾病(COPD)有关,所述疾病优选与肺动脉高压症状无关。此外,本发明公开了所述肽在另一种急性(成人)呼吸窘迫综合征(ARDS)的肺部疾病中的用途。可以证明,已知的天然存在的肽“血管活性肠肽(VIP)”和“垂体腺苷酸环化酶激活多肽(PACAP)”以及VIP和PACAP的类似物或衍生物可以成功地用于治疗所述疾病。 。

著录项

  • 公开/公告号IN2004DN01896A

    专利类型

  • 公开/公告日2007-04-06

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN1896/DELNP/2004

  • 发明设计人 DORIAN BEVEC;

    申请日2004-07-02

  • 分类号A61K38/22;

  • 国家 IN

  • 入库时间 2022-08-21 20:58:17

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