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A NOVEL PROCESS FOR PREPARING SUBSTANTIALLY ENANTIOMERICALLY PURE (+)ALPHA-ETHYL1-2-OXO-PYRROLIDINEACETIC ACID(-)ALPHA-ETHYL-2-OXO-PYRROLIDINEACETIC ACID AND (S)-ALPHA-ETHYL-2-OXO-PYRROLIDINEACETANIDE
A NOVEL PROCESS FOR PREPARING SUBSTANTIALLY ENANTIOMERICALLY PURE (+)ALPHA-ETHYL1-2-OXO-PYRROLIDINEACETIC ACID(-)ALPHA-ETHYL-2-OXO-PYRROLIDINEACETIC ACID AND (S)-ALPHA-ETHYL-2-OXO-PYRROLIDINEACETANIDE
A novel process for preparing substantially enantiomerically pure (+)-alpha-ethyl-2-oxo-pyrrolidineacetic acid (II) and (-)-alpha-ethyl-2-oxo-pyrrolidineacetic acid (III), which in tum is used to prepare a active pharmaceutical ingredient in its acceptable form )S)-alpha-ethyl-2-oxo-pyrrolidineacetamide (IV) and its pharmaceutical compositions may be used as a protective agent for the treatment and prevention of hypoxic ischemic type aggressions of the central nervous system. It is also effective in the treatment of epilepsy.
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