Rotavirus vaccine (live, oral solution) and its pharmaceutically acceptable derivatives (rotateq)

摘要

The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. The reassortant contains at least the gene encoding the vp3 neutralization antigen of bovine rotavirus of the WC3 strain and the gene encoding the vp7 neutralization antigen of a selected human rotavirus.