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derivatives of n - (3 - diphenyl - 1 - 3 - pyrazol) sulfonamide with affinite for cb1 receptors

机译:对cb1受体具有肯定性的n-(3-二苯基-1-3-[吡唑)磺酰胺的衍生物

摘要

The subject of the present invention is compounds corresponding to formula (I): Process for preparation and application in therapy in which: Ri represents A (Ci-C6) alkyl;1. ("C3-C7") is not substituted or substituted once or more naphthenic groups;1. (+ C3-C7) has no once or more substituted or substituted cycloalkylmethyl;1. Non substituted or substituted phenyl;1. Non substituted or mono substituted benzyl or disubstituted benzyl;1. Non substituted or substituted thiophene group;RI is the hydrogen atom or alkyl group ("ci-c3");R3 is a hydrogen atom or an alkyl group ("Ci CS");R4, R5, RO, R7, R "and R9 represent a hydrogen atom, a halogen atom, a (- ci-c7) alkyl group, a (- C = 124; - C5a!! 2. Coxy, trifluoromethyl radical or s() nalk group;N is 0, 1 or 2;Alk represents a (Ci-C4) alkyl. Method of preparation and application in therapy.
机译:本发明的主题是对应于式(I)的化合物:制备和应用在治疗中的方法,其中:Ri表示A(C 1 -C 6)烷基; 1。 (“ C3-C7”)未被取代或被一个或多个环烷基取代; 1。 (+ C3-C7)不具有一次或多次取代或取代的环烷基甲基; 1。非取代或取代的苯基; 1。非取代或单取代的苄基或二取代的苄基; 1。非取代或取代的噻吩基团; RI是氢原子或烷基(“ ci-c3”); R3是氢原子或烷基(“ Ci CS”); R4,R5,RO,R7,R”和R 9代表氢原子,卤素原子,(-C 1 -C 7)烷基,(-C = 124; -C 5a !! 2.氧,三氟甲基或s()烷基; N为0、1或2; Alk表示(C 1 -C 4)烷基,其制备方法和在治疗中的应用。

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