For the program and equipment of the production that the woven composite arrangement of reinforcement main body and TOPIC in space are obtained by program

摘要

The present invention relates to the compound of a chemical formula I or one pharmaceutically acceptable salt,Wherein 1 R 2 of Z or 1 or NR, wherein each R 1 and R 2 are independently H or a hydrocarbyl group; X is an olefin(e), alkenylene or alkynylene, each can optionally be replaced by one or more substituent groups selected from alkyl, COOH, CO 2- alkyl, alkenyl, CN, NH 2, hydroxyl, halation, alkoxy, CF 3 and nitro; Y is the polar functional group selected from OH, 2 numbers CN, 2 NR of COR 3, COOR 3, NR 3 R 4, CONR 3 R 4, SO 3 H, SO 2-R 3, SO, 3 R 4 and CF 3, wherein each R 3 and R 4 are independently H or a hydrocarbyl group; A is an aryl or heterocycle, each can selectively be substituted; WithB is (CH 2) n, and wherein n is 0,1,2,3,4 or 5; Condition:(i) when A is phenyl, n is 0, Z is OH, does is X-Y different from member C ‰? 2 H of C (CH 2) 2 CO, first C ‰? C (CH 2) 2 OH, first C ‰? 2 Me, meta-(CH 2 of C (CH 2) 2 CO) 4 CO, 2 H, 2 CO of n- CH, 2 H, n- 2 H of (CH 2) 2 CO and n- 2 H of (CH 2) 4 CO; WithDoes is (ii) n that 0, Z is OMe, and X-Y is different from member C ‰ when A is phenyl? 4 OH of C (CH 2). Other each aspect of the present invention is related to using for treating a muscular disorder, a gastrointestinal disorder, or such compound in a kind of preparation process of medicament for controlling spasticity or vibration.