Methods of treating diseases of cell proliferation, and a disorder associated with the activity of cinesina KSP, method for inhibition of cinesina KSP, compound.Method for screening of modulators of cinesina KPS, and screening method of compounds that bind to the cinesina KSP

摘要

Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associatged with KSP kinesin activity.