Playwright and composer of the niacin receptor

摘要

It refers to a first-order cyclododecyl derivative, where x is CH2, O, s, s (o),SO2, among others; R6 is an alternative to one to three groups of C1-C3 tar, in which 0 to 3 groups are halogen, 0 to 1 groups are C1-C3 tar, oh, NH2, etc.; a and B are 1, 2 or 3, so the sum of a and B is 2, 3 or 4; a ring is arilo of 6 to 10 members, 5-13 members or some aromatic non biological cycloliths; R2 and R3 are h, C1-C3 tar, C1-C3 halide, F, etc.; n is 1-5 integer; R4 is h, halo, R6; R5 is COOH, C (or) nhs2re, etc.; re is C1-C4 tar, phenyl, etc.; R1 is h, halo, oh, CN, NH2, etc,There are others A pharmaceutical composer was also mentioned These compounds are the enhancers of niacina receptor and useful tools for the treatment of carcinogenicity, degreasing, diabetes and so on.