Method and kit for assessing the risk of developing cancer of the pru00d3stata through analysis of specific polymorphisms in the 3 'UTR region of the gene of hepsina

摘要

This invenu00c7u00c3o has as main objective to establish a method to study, through specific analysis of the polymorphisms identified in the gene of hepsina, if a person has a predisposiu00c7u00c3o or an increased susceptibility to the development of cancer of the pru00d3st ATA. Another aim is to establish a kit that enables and facilitates the implementation of this analysis,.The presence of one or both of the amendments, NT c1568 g T and NT c1748 T C (nucleotu00cddica position based on cDNA of hepsina: nm _ 002151) in DNA genu00d3mico of a given individual indicates that this has a strong predisposiu00c7u00c3o gene to the development of cancer of the pru00d3stata, which shall Be subjected to increased surveillance.This method allows the identification of specific molecular changes with predictive value for cancer of the pru00d3stata, a broad group of individuals and with a relatively low cost.