polysaccharides extracted from skin of a skate (raja radula: extraction, purification, characterization of physicochemical and anticoagulant activity

摘要

the polysaccharides extracted from the skin of a skate (raja radula, from the fraction sia (substances insoluble in alcohol) by enzymatic digestion or acid hydrolysis and physicochemical characterization of a hyaluronic acid, dermatan sulfate.the anticoagulant activity of polysaccharides from the skin of the skate (raja radula from dermatan sulfate is very significant in comparison with heparin.these polysaccharides may give rise to several applications in biomedical and other substances, in particular as an anticoagulant and antithrombotic agents in the pharmaceutical industry, but also to other properties, mainly in the cosmetic industries and agro food re.