METHOD FOR PREVENTING GEL FORMATION OF TEVERELIX, SUSPENSION OF TEVERELIX (VARIANTS), METHOD FOR PRODUCING COMPOSITION AND SUSPENSION OF TEVERELIX

摘要

The invention relates to a method of preventing gel formation of hydrophobic peptides by contacting the hydrophobic peptide with a counter-ion in an amount and at a molar ratio sufficient to provide a fluid, milky microcrystalline aqueous suspension of the peptide without formation of a gel. The invention also relates to a fluid, milky microcrystalline aqueous suspension of a hydrophobic peptide and a counter-ion in water, wherein the peptide and counter-ion are present in amounts and at a molar ratio sufficient to form, upon mixing, the suspension without formation of a gel.