首页>
外国专利>
HYPER-BRANCHED AMYLOPEKTIN FOR USE IN SURGICAL PROCESSES FOR SURGICAL OR THERAPEUTIC TREATMENT OF ANIMALS OR IN DIAGNOSTIC PROCEDURES, IN PARTICULAR FOR USE AS PLASMA VOLUME EXPO
HYPER-BRANCHED AMYLOPEKTIN FOR USE IN SURGICAL PROCESSES FOR SURGICAL OR THERAPEUTIC TREATMENT OF ANIMALS OR IN DIAGNOSTIC PROCEDURES, IN PARTICULAR FOR USE AS PLASMA VOLUME EXPO
展开▼
机译:超支化淀粉蛋白,用于动物的外科或外科治疗或诊断过程中,特别是用作血浆体积博览会
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention relates to the use of hyperbranched amylopectin which has an average branch degree of between 10 and 25 mol % and a molecular weight (Mw) ranging from 40.000-800.000 Dalton and the derivatives thereof in methods for surgical or therapeutic treatment of human or animal bodies or in a diagnostic method, preferably as a plasma volume expander. Plasma volume expanders based on hydroxy-ethylated amylopectin have, as a result of hydroxy ethylation, hitherto exhibited the disadvantage of incomplete metabolism and thus temporary tissue storage which is linked to side-effects. According to the invention, novel plasma expanders based on polysaccharides which do not exhibit the same disadvantages as the former are provided. Improved, completely metabolised plasma expanders based on hyperbranched amylopectin which can be obtained therefrom so that native plant-amylopectins are altered-by transglycosylation in such a way the adjustable, high degree of branching enables control of the serum-alpha-amylase decomposition so that no or only a very insignificant degree of hydroxy ethylation is necessary.
展开▼