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ORAL PHARMACEUTICAL PREPARATION UNDERSTANDING AN ANTIQULCEROUS ACTIVITY COMPOUND AND PROCEDURE FOR OBTAINING IT.
ORAL PHARMACEUTICAL PREPARATION UNDERSTANDING AN ANTIQULCEROUS ACTIVITY COMPOUND AND PROCEDURE FOR OBTAINING IT.
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机译:口服药物制剂应理解其抗酸活性成分及获得过程。
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摘要
It comprises an inert core; a soluble or rapidly disintegrating active layer in water obtained from a single aqueous or hydroalcoholic suspension solution comprising: an active principle of antiulcer activity of formula (I, II or III), and at least one excipient; and a gastro-resistant outer coating layer obtained from a solution comprising: an enteric coating polymer; and at least one excipient. The procedure is carried out by 1) a coating of the inert nuclei by the nebulization of the only suspension-aqueous or hydroalcoholic solution; 2) a drying of the active layer formed during the fogging of the previous stage; and 3) a coating of the charged cores by nebulizing a solution comprising an enteric coating polymer with at least one excipient to obtain a gastro-resistant outer coating layer.
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