A MULTICOMPONENT VACCINE CONTAINING CLOSTRIDIAL AND NON-CLOSTRIDIAL ORGANISMS IN A LOW DOSE.

摘要

A multi-component ruminant vaccine comprising a safe and immunogenically effective combination of a protective antigenic component from a clostridial organism, a protective antigenic component from a non-clostridial organism and an adjuvant, in which the vaccine is in a dose volume is lowered at 3.0 ml or less and in which the adjuvant is selected from the group consisting of a polymer, a block copolymer, an oil in water, a water in oil, Al (OH) 3, AlPO3 and a wall extract Bacterial cell, a liposome, Quil A and a combination thereof.