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TISSUE-TYPE PLASMINOGEN ACTIVATOR (T-PA) INHIBITORS WITH A THERAPEUTIC CAPACITY

机译:具有治疗能力的组织型纤溶酶原抑制剂(T-PA)抑制剂

摘要

The invention relates to the tissue-type plasminogen activator (t-PA) which is a serine protease that is overexpressed in various different types of tumours, including cancer of the pancreas, melanomas and neuroblastomas. More specifically, the invention relates to t-PA activity and expression inhibitors that have been developed as antitumour agents.
机译:本发明涉及组织型纤溶酶原激活物(t-PA),其是丝氨酸蛋白酶,其在各种不同类型的肿瘤(包括胰腺癌,黑素瘤和神经母细胞瘤)中过表达。更具体地,本发明涉及已经开发为抗肿瘤剂的t-PA活性和表达抑制剂。

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