首页> 外国专利> METHOD FOR EVALUATING THE EFFECT OF AN ANGIOGENESIS INHIBITOR THROUGH THE INHIBITION OF INTEGRINE EXPRESSION.

METHOD FOR EVALUATING THE EFFECT OF AN ANGIOGENESIS INHIBITOR THROUGH THE INHIBITION OF INTEGRINE EXPRESSION.

机译:通过抑制整合素表达来评估血管生成抑制剂的作用的方法。

摘要

Method for assessing the influence of a drug on the expression of integrin, which comprises the stage at which the amount of integrin expression is measured in platelets collected from a patient to whom the drug is administered and the stage at which it is determined the influence of the drug on the expression of integrin in cells that are not platelets based on the reduction of the amount of expression measured, in which the integrin is integrin a2, and the cells are cells of a tissue in which it can be produce angiogenesis or tumor cells.
机译:评估药物对整联蛋白表达的影响的方法,该方法包括在从施用该药物的患者收集的血小板中测量整联蛋白表达量的阶段以及确定该药物对整联蛋白影响的阶段。根据测得的表达量减少来确定药物在不是血小板的细胞中表达整联蛋白的情况,其中整联蛋白是整联蛋白a2,并且该细胞是可以在其中产生血管生成或肿瘤细胞的组织的细胞。

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