METHOD FOR REDUCING INTRAOCULAR PRESSURE IN THE MAMMALIAN EYE BY ADMINISTRATION OF POTASSIUM CHANNEL BLOCKERS

摘要

Pharmaceutical compositions and a method are disclosed for treating glaucomaand/or ocular hypertension in the mammalian eyeby administering to the mammalian eye the pharmaceutical composition of theinvention which contains, as the active ingredient, oneor more compounds having potassium channel blocking activity. Examples ofpotassium channel blockers utilized in the pharmaceuticalcomposition and method of treatment are quinine, tremogenic indole alkaloids,such as Penitrem A and paspalicine, and insect toxins such ias charybdotoxin and iberiotoxin.