PHARMACEUTICAL PREPARATION CONTAINING AN ACETYLCHOLINESTERASE IHIBITOR AND AN ANTIDEPRESSANT WITH 5-HT AND ALPHA-2-ADRENOCEPTOR BLOCKING PROPERTIES.

摘要

The present invention relates to a pharmaceutical combination consisting of anacetylcholinesterase inhibitor drug (rivastigmine, donepezil or galantamine)and a serotoninergic (5-HT) and alpha-2 adrenergic (mirtazapine or mianserin)receptors blocker antidepressant. The preparation is useful for the treatmentof painful syndromes with increased efficacy and better tolerability than thedrugs alone. It is useful for the treatment of dementia with bettertolerability than the anticholinesterase drug alone and for the treatment ofdementia associated with depression or depressive symptoms.