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Canine tumor treatment method, pharmaceutical formulation applied thereto, and method of cryogenically preserving cells used therewith
Canine tumor treatment method, pharmaceutical formulation applied thereto, and method of cryogenically preserving cells used therewith
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机译:犬肿瘤的治疗方法,应用于其的药物制剂以及与其一起使用的低温保存细胞的方法
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摘要
A treatment for tumorous canines and a method of preparing, cultivating, and cryogenically preserving the pharmaceutical formulation used in the treatment. Canine lymphocytes are activated and expanded in the presence of a combination of anti-canine CD3 antibodies and interleukin-2 (IL-2) (preferably anti-canine CD3 antibodies and human interleukin-2 (human IL-2)) and administered to tumorous dogs. Following treatme-nt, the canine tumors were observed to be in regression while no serious side effects were noted. Quality-of-life improvements were observed in the form of the animals' ability to walk increased distances and improved coat appearance.
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