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Use of beta-hydroxy-beta-methylbutyrate to modulate the imbalance in type and type 2 cytokine production
Use of beta-hydroxy-beta-methylbutyrate to modulate the imbalance in type and type 2 cytokine production
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机译:使用β-羟基-β-甲基丁酸酯调节2型和2型细胞因子产生的不平衡
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摘要
Disclosed are methods of treating an individual having asthma wherein the method comprises administering to the individual an amount of ²-hydroxy-²-methylbutyrate (HMB) effective to modulate or otherwise cause an increase in the ratio of type (1) to type (2) cytokines, including an increase in the ratio of type (1) to type (2) cytokines without a corresponding increase in type (2) cytokine levels. The methods of the present invention arc based upon the discovery that HMB modulates cytokine production, most typically by increasing type (1) cytokines without a corresponding increase in type (2) cytokines.
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