COMPOSITIONS CONTAINING POLICOSANOL AND NIACIN AND/OR NIACIN DERIVATIVES AND THEIR PHARMACEUTICAL USES

摘要

A composition is provided which contains policosanol and niacin and/or niacin derivatives and which may be used for treating and or reducing hypercholesterolemic diseases, total cholesterol, LDL-cholesterol, LDL/HDL ratio, Lp(a), triglycerides, coronary heart disease (heart attacks and strokes), inflammation, immunoregulatory diseases, cardiovascular diseases, deep vein thrombosis, anxiety, depression and/or neurodegenerative disorders, and/or raise HDL cholesterol in humans and animals. The method comprises administering policosanol and niacin and/or niacin derivatives which together effectively lower the LDL/HDL cholesterol ratio. Typically, the administered composition includes about 0.1-10:1 parts by weight of policosanol to niacin and/or niacin derivatives.