MR CORONARY ANGIOGRAPHY WITH A FLUORINATED NANOPARTICLE CONTRAST AGENT AT 1.5 T

摘要

Disclosed herein is a medical imaging technique that uses a fluorinated nanoparticle contrast agent for imaging of an interior portion of a body. The fluorinated nanoparticles preferably comprise nontargeted intravascular fluorocarbon or perfluorocarbon nanoparticles. The interior body portion may be a patient's vasculature, and the medical imaging is preferably noninvasive MR angiography, which may encompass (either for 2D imaging or 3D imaging) MR coronary angiography, MR carotid angiography, MR peripheral angiography, MR cerebral angiography, MR arterial angiography, and MR venous angiography. Coils tuned to match to the SUP19/SUPF signal can be used, or dual tuned coils for SUP19/SUPF andSUP1/SUPH imaging can be used. Clinical field strengths (e.g.. 1.5T) and clinical doses may be used while still providing effective images.