PHARMACEUTICAL COMPOSITION COMPRISING SUBSTANCE CAPABLE OF INHIBITING OR PROMOTING PROGRANULIN ACTIVITY AND SCREENING METHOD FOR SUBSTANCE CAPABLE OF INHIBITING OR PROMOTING PROGRANULIN ACTIVITY

摘要

A pharmaceutical composition for the treatment or prevention of a disease induced by the increased fat tissues/cells and/or a disease induced by the increased macrophage activity, the pharmaceutical composition comprising a substance capable of inhibiting a progranulin activity; a pharmaceutical composition for the treatment or prevention of a disease induced by the decreased fat tissues/cells and/or a disease induced by the decreased macrophage activity, the pharmaceutical composition comprising progranulin and/or a substance capable of promoting a progranulin activity; a method for screening a substance capable of inhibiting or promoting a progranulin activity; a substance provided by the method; and others.