HYDROXYLATED FORMS OF ERGOSTEROLS AND ERGOCALCIFEROLS, DERIVATIVES THEREOF, METHODS OF PRODUCTION AND USES THEREOF

摘要

Provided herein is an enzymatic method of producing hydroxylated ergosterols and hydroxylated ergocalciferols using the cytochrome P450scc enzyme and/or the CYP27B1 enzyme and the hydroxylated compounds so produced. Also provided are methods of using the hydroxylated ergosterols and hydroxylated ergocalciferols to treat a tumor or other pathophysiologic condition.