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Process for the synthesis of ¬2S, 3aR, 7aS-octahydroindole-2-carboxylic acid and its conversion to trandolapril
Process for the synthesis of ¬2S, 3aR, 7aS-octahydroindole-2-carboxylic acid and its conversion to trandolapril
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机译:¬2S,3aR,7aS |-八氢吲哚-2-羧酸的合成及其转化为川多普利的方法
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摘要
The present invention describes a novel method for the synthesis of (2S,3aR,7aS)-octahydroindole-2-carboxylic acid of formula IIIusing a new intermediate of formula IIand conversion of the product of formula-III to trandolapril of formula I展开▼
机译:本发明描述了合成式III的(2S,3aR,7aS)-八氢吲哚-2-羧酸的新方法 <图像文件=“ IMGA0001.GIF” he =“ 29” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” wi =“ 43” /> Chemistry>使用式Ⅱ的新中间体 <图像文件=“ IMGA0002.GIF” he =“ 34” id =“ ia02” imgContent =“ chem” imgFormat =“ GIF” wi =“ 40” /> Chemistry>式III的产物转化为式I的trandolapril <图像文件=“ IMGA0003.GIF” he =“ 41” id =“ ia03” imgContent =“ chem” imgFormat =“ GIF” wi =“ 69” /> Chemistry>
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