VARIANT OF THE HUMAN SV2A PROTEIN AND THE INFLUENCE THEREOF ON THE EPILEPSY TREATMENT RESPONSE

摘要

The invention relates to a variant of the human synaptic vesicular protein SV2A (SV2A variant) and to a method for identifying said variant and the DNA coding therefor. Said identification process is used to predict the efficacy of defined anti-epileptic agents. The invention also relates to methods for identifying anti-epileptic active ingredients which react with said SV2A mutants, and to methods for treating epileptics, using the SVA2 variant.