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MICROFLUIDIC CELLS WITH PARALLEL ARRAYS OF INDIVIDUAL DNA MOLECULES
MICROFLUIDIC CELLS WITH PARALLEL ARRAYS OF INDIVIDUAL DNA MOLECULES
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机译:具有单个DNA分子平行阵列的微流控细胞
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摘要
Nucleic acid arrays and methods of using nucleic acid arrays are disclosed The nucleic acids are bound on one or both nucleic acid ends to a flow cell containing a lipid layer to prevent nonspecific binding The length and conformation of the nucleic acid is then visualized by evanescent illumination of fluorescent labels associated with the nucleic acid microscopic observation The methods can be used to visualize nucleic acid-protein interactions, and other interactions that affect the length or conformation of the nucleic acid.
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