Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex

摘要

Provided is a process for preparing an optically active ruthenium-phosphine complex represented by the following formula (1): wherein L represents a bidentate ligand compound of a tertiary phosphine; X represents a halogen atom; and * means chiral center (L* is an optically active substance), which comprises reacting a ruthenium-phosphine complex represented by:        Ru_mX_nL_pA_q or [RuX(D) (L)]Xwherein, X and L have the same meanings as described above (L is a racemic modification); A represents triethylamine (Et₃N), etc. ; and m, n, p and q each stands for an integer and D represents benzene, etc. with 1/2 equivalent of a specific optically active chiral diamine, thereby inactivating one of the enantiomers; and then with a specific optically active diamine derivative, thereby activating the other enantiomer.