首页> 外国专利> WELL UNIT FOR DETECTING CELL CHEMOTAXIS AND SEPARATING CHEMOTACTIC CELLS

WELL UNIT FOR DETECTING CELL CHEMOTAXIS AND SEPARATING CHEMOTACTIC CELLS

机译:用于检测细胞趋化因子和分离化学趋化细胞的孔单元

摘要

The present invention aims at providing a well unit to be used in fabricating an apparatus whereby movements of cells based on their own actions can be accurately and easily detected, in detecting the chemotaxis of cells due to a chemotactic factor or the inhibition of the chemotaxis of cells by an inhibitor. Accordingly, the present invention provides a well unit to be used in an apparatus for detecting chemotaxis of cells and separating cells characterized in that a plural number of wells, in which a liquid sample can be held in a resting state, are connected to each other via a channel, the channel is provided with a bank, and, in the upper part of the bank, barriers constituting one or more grooves having a width and/or a depth fit for the diameter or deformability of cells are provided or a plane is provided so as to give a gap having a depth fit for the diameter or deformability of cells between the plane and the glass substrate.
机译:本发明的目的在于提供一种孔单元,该孔单元用于制造一种设备,从而在检测由于趋化因子引起的细胞趋化性或抑制细胞的趋化性而检测细胞的趋化性时,能够基于细胞自身的作用准确而容易地检测细胞的运动。细胞被抑制剂抑制。因此,本发明提供了一种用于细胞的趋化性检测和细胞分离的装置中的孔单元,其特征在于,多个可以将液体样品保持在静止状态的孔相互连接。经由通道,该通道设置有堤,并且在堤的上部中,提供了构成一个或多个凹槽的阻挡层,该凹槽的宽度和/或深度适合于电池的直径或可变形性,或者平面为了在平面和玻璃基板之间提供孔,该间隙具有深度以适合孔的直径或可变形性。

著录项

  • 公开/公告号EP1340809A4

    专利类型

  • 公开/公告日2007-04-04

    原文格式PDF

  • 申请/专利权人 EFFECTOR CELL INSTITUTE;

    申请/专利号EP20010999630

  • 申请日2001-12-06

  • 分类号B01L3;B81B1;B81C99;G01N15/14;G01N33/50;G01N33/53;

  • 国家 EP

  • 入库时间 2022-08-21 20:49:35

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