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PHARMACEUTICAL COMPOSITIONS WITH WOUND HEALING OR ANTI-COMPLEMENTARY ACTIVITY COMPRISING A DEXTRAN DERIVATIVE

机译:具有Dextran衍生物的伤口愈合或抗补充活性的药物组合物

摘要

The invention concerns pharmaceutical compositions with wound healing or anti-complementary activity, and their uses, said compositions comprising, (1) at least a dextran derivative of general formula DMCSUBa/SUBBSUBb/SUBSuSUBc/SUB, a, b, and c respectively representing the degrees of substitution in the groups MC, B and Su, wherein a=0.6, b=0 or =0.1, and c=0 or ranges widely between 0.1 and 0.5 for a wound healing composition, and a=0.3, b=0.1 and c=0 or ranges widely between 0.1 and 0.4 for a composition with anti-complementary activity; (2) and at least a pharmaceutically acceptable carrier, said dextran derivative being present in a single unit dose or at a concentration adapted to the desired wound healing or anti-complementary activity.
机译:本发明涉及具有伤口愈合或抗补体活性的药物组合物及其用途,所述组合物包含(1)至少通式为DMC a B b Su c ,a,b和c分别表示组MC,B和Su中的取代度,其中a> = 0.6,b = 0或> = 0.1,且c = 0对于伤口愈合组合物,或在> 0.1至0.5的范围内,并且对于具有抗互补活性的组合物,a> = 0.3,b> = 0.1和c = 0,或在0.1至0.4的范围内; (2)和至少一种药学上可接受的载体,所述葡聚糖衍生物以单一单位剂量或以适合于所需伤口愈合或抗互补活性的浓度存在。

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