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USE OF 8-ALPHA-ERGOLINES FOR THE TREATMENT OF TRAUMATIC BRAIN DISORDERS

机译:使用8-α-麦角灵治疗创伤性脑疾病

摘要

The present invention relates to 8-a-ergoline derived compounds and salts, enantiomers, mixtures of enantiomers, diastereomers, mixtures of diastereomers, hydrates, solvates and racemates and/or pharmaceutically acceptable salts of these compounds for use in pharmaceutical compositions together with pharmaceutically acceptable carriers, excipients and/or diluents. Said 8-a-ergoline derived compounds are useful for the preparation of pharmaceutical compositions for the treatment and/or prophylaxis of epileptic seizures, increased cranial pressure and brain edema in the acute or rehabilitation phase of a brain injury.
机译:本发明涉及用于药物组合物中的8-α-麦角灵衍生的化合物和盐,对映异构体,对映异构体混合物,非对映异构体混合物,非对映异构体混合物,水合物,溶剂化物和外消旋物和/或药学上可接受的盐和/或药学上可接受的盐载体,赋形剂和/或稀释剂。所述8-α-麦角灵衍生的化合物可用于制备药物组合物,用于在脑损伤的急性或康复阶段中治疗和/或预防癫痫发作,增加的颅压和脑水肿。

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