THE 3D POROUS LAYERED SCAFFOLD FOR TISSUE ENGINEERING AND THE PREPARATION THEREOF

摘要

The 3D porous layered scaffold for tissue engineering and the preparation thereof. Bioabsorbable polylactic acid, polyglycolic acid and copolymer thereof, polycaprolactone and the like, and chitosan, chondroitin sulfate, collagen, heparin sulfate, sodium alginate, hyaluronic acid and the like are used as the matrix material, and assemble medical polymer with anion or cation charge such as chitosan, chondroitin and the like onto the surface of special cylindrical core by the technology of nanometer self-assembly, followed by vacuum drying and freeze drying, and a highly biomimetic human tubular scaffold is obtained which can be regulated in structure, size and shape.