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METHODS AND COMPOSITIONS FOR ENHANCEMENT OF IMMUNITY BY IN VIVO DEPLETION OF IMMUNOSUPPRESSIVE CELL ACTIVITY

机译：通过体内抑制免疫抑制细胞活性增强免疫力的方法和组合物

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摘要

The present invention provides a method of enhancing an immune response in a subject, comprising administering to the subject a reagent that targets a cell having immunosuppressive activity, in an amount effective in reducing the immunosuppressive activity of the cell, thereby enhancing an immune response in the subject. Also provided are methods of treating cancer and infection in a subject by administering the reagents of this invention to a subject.

机译：本发明提供了一种在受试者中增强免疫应答的方法，其包括以有效降低所述细胞的免疫抑制活性的量向所述受试者施用靶向具有免疫抑制活性的细胞的试剂，从而增强所述受试者的免疫应答。学科。还提供了通过向受试者施用本发明的试剂来治疗受试者的癌症和感染的方法。

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公开/公告号EP1765402A2

专利类型
公开/公告日2007-03-28

原文格式PDF
申请/专利权人 DUKE UNIVERSITY;
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申请/专利号EP20050856785
发明设计人 VIEWEG JOHANNES W.;
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申请日2005-06-03
分类号A61K39/395;C12N15/31;C12N15/62;C07K16/28;C12N15/09;
国家 EP
入库时间 2022-08-21 20:45:09

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