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NPC1L1 AND NPC1L1 INHIBITORS AND METHODS OF USE THEREOF
NPC1L1 AND NPC1L1 INHIBITORS AND METHODS OF USE THEREOF
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机译:NPC1L1和NPC1L1抑制剂及其使用方法
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摘要
The present invention provides a novel gene, designated herein as “NPC1L1”, that is associated with lipid or glucose metabolism. The invention further provides the use of the NPC1L1 gene and its corresponding protein to diagnose a lipid condition in a cell or tissue and to screen for novel therapeutic compounds useful for treating lipid disorders and other NPC1L1-associated or mediated diseases or disorders. The invention further provides specific inhibitors of NPC1L1.
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