Surface modification of optical elements for the spectroscopic detection of molecules and organic components

摘要

The invention relates to a device suitable for the investigation of ligand-receptor interactions, in particular for the investigation of an analyte target interaction such as biological and chemical molecules and organic components and their interaction with surfaces consisting of an attenuated total internal reflection element, transparent in the infra-red and of which at least one surface is reduced and covalently grafted with an optionally substituted alkene able to immobilize the receptor.