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New Polypeptides from Haemophilus paragalinarum and Methods for Making the Same

机译:副猪嗜血杆菌的新多肽及其制备方法

摘要

A novel polypeptide from Haemophilus paragallinarum useful for prevention of avian infectious coryza is provided. A novel polypeptide from Haemophilus paragallinarum which induces production of HI antibody and prevents infection and onset of avian infectious coryza, a gene coding for said polypeptide, a recombinant vector for expression of said gene, a host transformed with said vector, a process for preparing said polypeptide wherein said polypeptide is produced by said host, a vaccine for avian infectious coryza comprising as an active ingredient said polypeptide, a monoclonal antibody obtained by using said polypeptide as an immunogen and a diagnostic agent and a therapeutic agent for avian infectious coryza utilizing said peptide and said antibody.
机译:提供了可用于预防禽传染性鼻炎的副鸡嗜血杆菌的新型多肽。来自副鸡嗜血杆菌的新型多肽,其诱导HI抗体的产生并防止禽传染性鼻虫的感染和发作,编码所述多肽的基因,用于表达所述基因的重组载体,用所述载体转化的宿主,制备所述方法其中所述多肽是由所述宿主产生的多肽,包含所述多肽作为活性成分的禽传染性鼻炎疫苗,通过使用所述多肽作为免疫原而获得的单克隆抗体和利用所述肽的禽传染性鼻炎诊断剂和治疗剂和所说的抗体。

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