Composition containing antimicrobial peptide buforin derivatives

摘要

PURPOSE: An antimicrobial composition containing buforin derivatives as an antimicrobial peptide is provided which can be used as medicine, animal medicine, living article, biopesticide, feed additives, etc. because it exhibits almost no toxicity while retaining wide antimicrobial activity against aerobic and anaerobic bacteria and bacteria. CONSTITUTION: This composition contains one or more peptides selected from the group consisting of peptides containing an amino acid sequence of SEQ ID NO: 1, an amino acid sequence of SEQ ID NO: 2 and sequences thereof and also treats diseases caused by bacteria. Buforin IIb as buforin derivatives exhibits an excellent antimicrobial activity against aerobic Gram-positive bacteria and Gram-negative bacteria, anaerobic bacteria and fungus containing a variety of drug-resistant bacteria.