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Method of predicting survival of a non-small-cell lung cancer patient to a chemotherapeutic treatment

机译：预测非小细胞肺癌患者化疗治疗生存率的方法

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摘要

Method for predicting the survival of a patient suffering from NSCLC to an antimicrotubule agent based chemotherapy treatment which comprises the step of determining the methylation state of a nucleic acid encoding CHFR in a biological sample from the patient, wherein the presence of methylation is indicative of longer survival of said patient as a response to said chemotherapy treatment. The methylation status of the CHFR gene can be easily determined in a serum sample.

机译：预测患有NSCLC的患者对基于抗微管剂的化学疗法治疗的存活的方法，其包括确定来自患者的生物样品中编码CHFR的核酸的甲基化状态的步骤，其中甲基化的存在指示更长的时间所述患者的存活率作为对所述化学疗法治疗的反应。在血清样品中， CHFR 基因的甲基化状态很容易确定。 展开▼

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公开/公告号EP1840224A1

专利类型

公开/公告日2007-10-03

原文格式PDF

申请/专利权人 PANGAEA BIOTECH S.A.;
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申请/专利号EP20060075767

发明设计人 ROSELL COSTA RAFAELINSTITUT CATALÀ DONCOLOGÍA;TARÓN ROCA MIGUELINSTITUT CATALÀ DONCOLOGÍA;
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申请日2006-03-29

分类号C12Q1/68;A61K31/337;

国家 EP

入库时间 2022-08-21 20:38:20

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