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Remedies or Preventives for Pulmonary Insufficiency Containing Diaminotrifluoromethylpyridine Derivatives
Remedies or Preventives for Pulmonary Insufficiency Containing Diaminotrifluoromethylpyridine Derivatives
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机译:含二氨基三氟甲基吡啶衍生物的肺功能不全的补救措施或预防措施
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摘要
A therapeutic or preventive agent for pulmonary insufficiency, containing as an active ingredient a diaminotrifluoromethylpyridine derivative represented by the formula (I) or its salt: CHEM wherein X is a -CW1R1 group, a -COCOR2 group, a -CW1NHCOR2 group, a -C(=W1)W2R3 group or a -CW1N(R4)R5 group; Y is an alkyl group, a -CW3R6 group, a -COCOR7 group, a -NHCOR7 group, a -C(=W3)W4R8 group, a -(NH)mSO2R9 group, a -(NH)mSO2OR10 group or a -(NH)mSO2N(R11)R12 group; each of R1, R6 and R9 is a chain hydrocarbon group, a monocyclic hydrocarbon group, a polycyclic hydrocarbon group, a monocyclic heterocycle group or a polycyclic heterocycle group; each of R2 and R7 is an alkyl group, an alkoxy group, a phenyl group or a phenoxy group; each of R3, R8 and R10 is an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a phenyl group or a benzyl group; each of R4, R5, R11 and R12 is an alkyl group; each of W1, W2, W3 and W4 is an oxygen atom or a sulfur atom; and m is 0 or 1, is provided.
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机译:肺功能不全的治疗剂或预防剂,其包含由式(I)表示的二氨基三氟甲基吡啶衍生物或其盐作为活性成分:其中X是-CW 1 R 1基团,-COCOR 2>组,-CW <1> NHCOR <2>组,-C(= W <1>)W 2R 3组或-CW <1> N(R 4)R <5>组; Y为烷基,-CW 3 R 6基,-COCOR 7基,-NHCOR 7基,-C(= W 3)W 4 R 4。 8个基团,-(NH)mSO 2 R 9基团,-(NH)mSO 2 OR 10基团或-(NH)mSO 2 N(R 11)R 12基团; R 1,R 6和R 9分别为链状烃基,单环烃基,多环烃基,单环杂环基或多环杂环基。 R 2和R 7分别为烷基,烷氧基,苯基或苯氧基。 R 3,R 8和R 10分别为烷基,烯基,炔基,环烷基,苯基或苄基。 R 4,R 5,R 11和R 12分别为烷基。 W 1,W 2,W 3和W 4分别为氧原子或硫原子。并且提供m为0或1。
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