首页> 外国专利> Cancer cell-growth inhibition drugs comprising lamin A gene or lamin A protein, preparation method thereof and use thereof

Cancer cell-growth inhibition drugs comprising lamin A gene or lamin A protein, preparation method thereof and use thereof

机译:包含lamin A基因或lamin A蛋白的癌细胞生长抑制药物,其制备方法和用途

摘要

The present invention , one of the intermediate fiber lamin proteins attached to the lining of the nuclear envelope A (Lamin A) protein or this encryption lamin a cancer-cell proliferation inhibitor containing the gene (LMNA), relates to a method for inhibiting the proliferation of cancer cells using the same, and methods for their preparation . According to the present invention , the lamin A gene comprising the inhibitors in cancer cells were treated to obtain a low survival rate of 54% of the cancer cells , via the lamin A gene indicating valid for such cancer-cell proliferation inhibitory effect of the cancer-cell proliferation mechanism overall understanding , as well as cancer diagnostic reagent , is expected to be used in cancer treatment or the like useful for development .
机译:本发明是一种附着于核被膜A(Lamin A)蛋白的衬里的中间纤维层粘蛋白(lamin A)之一,或者该加密层粘蛋白(lamin)是含有该基因(LMNA)的癌细胞增殖抑制剂,涉及一种抑制增殖的方法使用该癌细胞的细胞及其制备方法。根据本发明,通过对癌症中的这种癌细胞增殖抑制作用有效的lamin A基因,对包含癌细胞中的抑制剂的lamin A基因进行处理,从而获得54%的低存活率。对细胞增殖机制以及癌症诊断试剂的总体了解,有望用于对发展有用的癌症治疗等中。

著录项

  • 公开/公告号KR100710549B1

    专利类型

  • 公开/公告日2007-04-24

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20020042098

  • 发明设计人 주홍신;조수진;장주현;김동수;

    申请日2002-07-18

  • 分类号A61K48/00;

  • 国家 KR

  • 入库时间 2022-08-21 20:32:23

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