首页> 外国专利> Compositions for inducing apoptosis comprising glycero-1,5-epoxy-1??,6-dihydroxy-cis-hex-3-en-2-one or derivative

Compositions for inducing apoptosis comprising glycero-1,5-epoxy-1??,6-dihydroxy-cis-hex-3-en-2-one or derivative

机译:诱导细胞凋亡的组合物,其包含甘油-1,5-环氧-1β,6-二羟基-顺式-hex-3-en-2-one或衍生物

摘要

CHEM Therapeutic or preventive agents for diseases requiring apoptosis induction, cancerous diseases, diseases requiring the inhibition of active oxygen production, those requiring the inhibition of nitrogen monoxide production, those requiring the inhibition of prostaglandin synthesis, those requiring the inhibition of synovial cell proliferation, those requiring the induction of heat shock protein production or those requiring the inhibition of alpha -glycosidase, which contain as the active ingredient compounds selected from among compounds represented by general formula (I), (wherein X and Y are each H or CH2OH, provided that when X is CH2OH, Y is H, while when X is H, Y is CH2OH), those represented by general formula (II), (wherein R is a residue obtained by freeing a compound having an SH group from the SH group) and salts of both; and foods, drinks, cosmetics and so on, containing compounds selected from among compounds of general formula (I), those of general formula (II) and salts of both.
机译:用于需要诱导凋亡的疾病,癌症疾病,需要抑制活性氧产生的疾病,需要抑制一氧化氮产生的疾病,需要抑制前列腺素合成的疾病,需要抑制滑膜细胞增殖的疾病的治疗或预防剂那些需要诱导热激蛋白产生的化合物或需要抑制α-糖苷酶的化合物,它们含有作为活性成分的化合物选自通式(I)表示的化合物(其中X和Y分别为H或CH 2 OH,前提条件是当X为CH 2 OH时,Y为H,而当X为H时,Y为CH 2 OH时,通式(II)表示的那些化合物(其中R为通过将具有SH基团的化合物与SH基团游离而获得的残基)。 )和两者的盐;以及食品,饮料,化妆品等,其包含选自通式(I)的化合物,通式(II)的化合物和两者的盐的化合物。

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