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COMPOSITION FOR INJECTION CONTAINING FLORFENICOL AND TYLOSIN

机译:注射用氟苯尼考和酪氨酸的组合物

摘要

Provided is a composition for injection containing florfenicol and tylosin which has improved stability by reducing viscosity and is able to inhibit solubility lowering of florfenicol and content lowering of tylosin during storage while high concentration of florfenicol is contained by using safe solvent. The composition for injection contains 15-30 wt.% of florfenicol, 2-8 wt.% of tylosin or veterinarily acceptable salts thereof, 30-70 wt.% of dimethylsulfoxide, 2-20 wt.% of propylene glycol and 5-30 wt.% of water, further contains 0.5-5 wt.% of benzyl alcohol or 0.01-0.5 wt.% of dexamethasone or veterinarily acceptable salts thereof, wherein the composition has viscosity of 1-10 cp.
机译:提供了一种含有氟苯尼考和泰乐菌素的注射用组合物,该组合物通过降低粘度而具有改善的稳定性,并且在通过使用安全溶剂包含高浓度的氟苯尼考时,能够在储存期间抑制氟苯尼考的​​溶解度降低和泰乐菌素含量的降低。注射用组合物包含15-30重量%的氟苯尼考,2-8重量%的泰乐菌素或其兽医学上可接受的盐,30-70重量%的二甲亚砜,2-20重量%的丙二醇和5-30重量%的水,进一步包含0.5-5重量%的苯甲醇或0.01-0.5重量%的地塞米松或其兽医学上可接受的盐,其中组合物的粘度为1-10cp。

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