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METHOD FOR ANALYSING SINGLE NUCLEOTIDE POLYMORPHISMS OF GERIATRIC DISEASES USING OLIGONUCLEOTIDE CHIP AND KIT THEREFOR
METHOD FOR ANALYSING SINGLE NUCLEOTIDE POLYMORPHISMS OF GERIATRIC DISEASES USING OLIGONUCLEOTIDE CHIP AND KIT THEREFOR
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机译:寡核苷酸芯片及其试剂盒分析老年性疾病的单核苷酸多态性的方法
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摘要
The invention hypertension, atherosclerosis, dementia, osteoporosis, single nucleotide polymorphisms existing in the adult disease-related genes, such as diabetic complications (Single Nucleotide Polymorphisms: hereinafter "SNPs" abbreviated as) test method and a test kit to be used therefor It relates. ; The present invention is the polymerase chain reaction of the gene to be examined: the step of amplifying using an (Polymerase Chain Reaction hereinafter "PCR"); Oligonucleotide containing the SNPs present in the adult disease related genes comprising oligonucleotides attached to the base is attached using the amplification product hybridization (hybridization) of the base chip; And inspection by using the SNPs inspection method comprising the steps to determine specifically bound SNPs in the hybridization reaction, rapid each adult SNPs of the relevant gene, accurately, and also checks the number of SNPs in the gene with a single scan of the same time can do. ; Adult diseases, gene polymorphism, examination methods, test kits.
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