ANTITUMOR COMPOSITION COMPRISING EXPRESSION VECTOR ENCODING IMPORTIN GENE AND RECOMBINAT p53 GENE

摘要

The present invention relates to an anti-cancer composition comprising the vector or the protein thereof that express the recombinant gene and the p53 α gene imported tin. ; Cancer search method of this using a mutant of imported tin α gene according to the invention are anti-cancer comprising a vector or its protein p53 is, and can search the non-mutated cancer cells, expression import tin α gene with the recombinant p53 gene by activating composition to normalization of the function of p53 induces apoptosis of cancer cells because it can be effective in anti-cancer therapy. ; p53, importing tin α, VP16, killing cancer cells, gene therapy