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Topical cosmetic and dermatological composition containing alkylurea and other active agent, useful for treating e.g. ageing of the skin and pigmentation disorders

机译:含有烷基脲和其他活性剂的局部化妆品和皮肤病学组合物,可用于治疗例如皮肤老化和色素沉着症

摘要

Topical cosmetic or dermatological composition (X) contains at least one hydroxyalkylurea (A) and at least one other active agent (B). Topical cosmetic or dermatological composition (X) contains at least one hydroxyalkylurea of formula (A) and at least one other active agent (B). R 1R 2N-CO-NR 3R 4 (A) (B) is: (a) a monomer, oligomer or polymer of (2-24C acyl) amino acids, their esters and/or metal salts; (b) DNA or RNA oligonucleotides; (c) natural betaines; (d) (pro)vitamins or their precursors of groups A, B, C, E, H or K and their esters; (e) alpha - or beta -hydroxy- or alpha -keto-carboxylic acids, or their esters, lactones or salts (excluding compositions containing 5wt.% 2-hydroxyethylurea and 0.05-5wt.% ammonium lactate or those containing 2-hydroxypropylurea and alpha - and/or beta -hydroxyacids); (f) specified flavonoids (e.g. naringin, alpha -glucosylquercitin, hesperidin or rutin); (g) isoflavonoids and plant extracts rich in them; (h) ubiquinone, ubiquinol and their derivatives; (i) silymarin; (j) natural xanthine derivatives, e.g. caffeine, theophylline, theobromine and aminophylline; (k) ectoin; (l) creatine; (m) olive leaf extracts, ursolic acid, olive oil and/or oleanolic acid; (n) mono- and poly-hydroxystilbenes and their esters; (o) derivatives of methylated silanol; (p) phytic acid; (q) maize or (r) oats kernel extracts; (s) Saccharomyces, xylinum, black tea ferment; (t) apple or (u) lotus seed extracts; (v) red wine extract; (w) grape seed extract, preferably of the Chardonnay strain; (x) extract of Sambucus nigra flowers; (y) agents that stimulate beta -endorphin synthesis in keratinocytes; (z) (in)organic UV filters; (aa) self-tanning agents; (bb) skin-lightening agents; (cc) agents that inhibit synthesis of prostaglandins (PG) and/or leukotrienes (LT); (dd) sebum-regulating agents and (ee) polysaccharides that contain deoxysugars or their components. R 1-R 4hydrogen, 1-4C alkyl, 2-6C hydroxyalkyl with 1-5 hydroxy groups, or 1-4C hydroxyalkyl, provided that at least one is hydroxyalkyl. ACTIVITY : Dermatological. No details of tests for dermatological activity are given. MECHANISM OF ACTION : None given.
机译:局部化妆品或皮肤病学组合物(X)包含至​​少一种羟烷基脲(A)和至少一种其他活性剂(B)。局部化妆品或皮肤病学组合物(X)包含至​​少一种式(A)的羟烷基脲和至少一种其他活性剂(B)。 R 1R 2N-CO-NR 3R 4(A)(B)为:(a)(2-24C酰基)氨基酸,其酯和/或金属盐的单体,低聚物或聚合物; (b)DNA或RNA寡核苷酸; (c)自然甜菜; (d)A,B,C,E,H或K组的(原)维生素或其前体及其酯; (e)α-或β-羟基或α-酮基羧酸,或其酯,内酯或盐(不包括含有5wt。%2-羟乙基脲和0.05-5wt。%乳酸铵的组合物或含有2-羟丙基脲的组合物和α-和/或β-羟基酸); (f)特定的类黄酮(如柚皮苷,α-葡萄糖基槲皮素,橙皮苷或芦丁); (g)异黄酮和富含它们的植物提取物; (h)泛醌,泛醌及其衍生物; (i)水飞蓟素; (j)天然黄嘌呤衍生物,例如咖啡因,茶碱,可可碱和氨茶碱; (k)胞外蛋白; (l)肌酸; (m)橄榄叶提取物,熊果酸,橄榄油和/或齐墩果酸; (n)单-和多-羟基苯乙烯酯及其酯; (o)甲基化硅烷醇的衍生物; (p)植酸; (q)玉米或(r)燕麦仁提取物; (s)酵母菌,木糖,红茶发酵液; (t)苹果或(u)莲子提取物; (v)红酒提取物; (w)葡萄籽提取物,最好是霞多丽菌株; (x)黑接骨木花的提取物; (y)刺激角质形成细胞中β-内啡肽合成的试剂; (z)有机紫外线过滤器; (aa)自晒黑剂; (bb)亮肤剂; (cc)抑制前列腺素(PG)和/或白三烯(LT)合成的试剂; (dd)皮脂调节剂和(ee)含有脱氧糖或其成分的多糖。 R 1 -R 4氢,1-4C烷基,具有1-5个羟基的2-6C羟烷基或1-4C羟烷基,条件是至少一个为羟烷基。活动:皮肤科。没有给出皮肤活性的测试细节。作用机理:未给出。

著录项

  • 公开/公告号DE102005026357A1

    专利类型

  • 公开/公告日2006-12-28

    原文格式PDF

  • 申请/专利权人 HENKEL KGAA;

    申请/专利号DE20051026357

  • 申请日2005-06-07

  • 分类号A61K8/49;A61Q19/06;A61Q19/08;A61Q17;A61K8/44;A61K8/67;A61K8/97;A61K8/34;A61K8/362;A61K8/66;A61K8/60;

  • 国家 DE

  • 入库时间 2022-08-21 20:29:56

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